Suzuki started manufacturing motorcycles in 1952, the first models being motorized bicycles. During the 1950's, 1960's and the better part of 1970's, the company manufactured motorcycles with two-stroke engines only, the biggest two-stroke model being the water-cooled triple-cylinder GT750. However, it wasn't until 1976 when Suzuki introduced its first motorcycle with a four-stroke engine, the GS400 and GS750. Since then, Suzuki has established a reputation as a manufacturer of well-engineered sport motorcycles.

In the 1970s, Suzuki also established itself in the racing world, winning several World Championships in Grand Prix motorcycle racing with Barry Sheene winning the 500cc Roadracing crown twice and Roger DeCoster winning the 500cc Motocross Grand Prix title five times.