Eicoosapentaenoic acid (EPA) and docosahexanaeic acid (DHA) are contained in omega 3 fatty acids (O3FA). O3FA sumpplements are mostly derivid from coldwater fish like salmon, sardines, herring, and mackerel. Some of the therapeutic benefits for O3FA are cardiovascular enhancement and as an anti-inflammatory supplement. Reseach in cardiovascular benefits include reducing the risk of atherosclerosis, modifying cholesterol levels (i.e. increasing "good" HDL cholesterol, while decreasing "bad" LDL cholesterol) decreasing triglycerides and decreasing high blood pressure O3FA have also been shown to block the production of certain inflammatory chemicals in our body. Studies have demonstrated the abilty of O3FA to reduce inflammation in such disorders as rheumatoid arthritis, astma, colitis,Crohn's disease, and Lupus. In addition, O3FA have shown to reduce the symptoms of other disorders including angina, migraine headaches, psoriasis, and tinnitus. Most fish oil supplements come in a mixture of 18% EPA and 12% DHA. Therefore in 1000 mg of fish oil there would be 180 mg EPA and 120 mg of DHA. However, it makes more sense to seek out more concentrated preparations, which will minimize the amount of fish oil you must consume, and help prevent the dreaded fish burp. Look for something in the 375mg EPA and 250mg DHA range providing 625mg of total omega 3 fatty acids. The doses recommended in the following conditions are based on the use of a supplement providing 625mg of total omega 3 fatty acids. Atherosclerosis 1-2 capsules daily Cholesterol & triglycerides 5 capsules daily. High blood presure 5 capsules daily. Rheumatoid arthritis 1-2 capsules daily. Asthma 1-2 capsules daily Colitis 1-2 capsules daily. Crohn's Disease 1-2 capsules daily Lupus 5-6 capsules three times a day However people wishing to take this high dose should first consult with a nutritionally oriented physician. Angina An effective dose would be 8 capsules daily However people wishing to take this high dose should first consult with a nutritionally oriented physician. Migraine 2-10 capsules daily. However people wishing to take this high dose should first consult with a nutritionally oriented physician. Psoriasis 8-9 capsules daily However people wishing to take this high dose should first consult with a nutritionally oriented physician. Tinnitus 1-2 capsules daiy http://cgi.ebay.com/ws/eBayISAPI.dll?ViewItem&sspagename=STRK%3AMESE%3AIT&viewitem=&item=270084139415&rd=1&rd=1 References Johansen O,et al. Arteriosoler ThrombVasc Biol (1999) 19(7):1681-6. Enikeeva NA, Kitaiskaia LS Antoniuk MV Khn Med (1999)77(3):25-8 von Schacky C, et al. Ann Intern Med (1999) 130(7):554-62 Sucic M. Katica D. Kovaeevie V. Coll Antropol (1998) Baumann KH, et al, Aterioscler Thromb Vasc Biol(1999) 19(1):59-66. Seljeflot I, et al. Thromb Haemost (1999)81(4):566-70 Santos MJ,Lopez-Jurado M. Llopis J. et al. 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