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N Acetyl Cysteine Information Antioxidants ClubNatural

by: clubnatural( 72920Feedback score is 50,000 to 99,999) Top 5000 Reviewer
1 out of 1 people found this guide helpful.
Guide viewed: 1038 times Tags: Acetyl | Cysteine | acetylcyteine | NAC | clubnatural


N Acetyl l cysteine (also spelled acetylcysteine, N Acetyl L Cysteine or N-acetylcyteine) is made from the amino acid cysteine joined to an acetyl group. Acetylcysteine (sometimes abbreviated as N-A-C  or NAC) is a strong antioxidant. It donates the amino acid cysteine to help form the antioxidant glutathione. Glutathione is a powerful antioxidant normally found in the body.
N Acetyl Cysteine is an amino acid and antioxidant. N Acetyl l cysteine is a precursor in the body to the critical antioxidant glutathione, which is produced within cells, particularly by the liver. Acetylcysteine is significantly more cost effective than taking glutathione.
Acetylcysteine Side Effects
Other than large doses causing nausea, acetylcysteine does not have any significant side effects and appears to be a safe nutrient as long as the dosage is kept to less than 500 mg.

Counteracting Tylenol Toxicity
Regular use of the painkiller acetaminophen is associated with higher rates of asthma and chronic obstructive pulmonary disease and reduced lung function. Animal experiments have suggested that acetaminophen might lower antioxidant activity in the lungs, and causes harm to the liver and kidneys. 
     With hundreds of people each year dying from acetaminophen overdose, thousands more with liver damage or other health problems, why is acetaminophen still available for sale without a prescription whereas regulators have tried to pull away certain nutritional supplements that are far less toxic?
     Those who need to take acetaminophen for a health condition should consider Acetylcysteine, a nutrient that protects the liver from this drug's toxicity. The antidote for acetaminophen poisoning is N acetyl cysteine. Acetylcysteine is thought to work through a number of protective mechanisms. Acetylcysteine is a precursor of glutathione and increases glutathione availability. Acetylcysteine also functions as an anti-inflammatory and antioxidant and has positive inotropic effects. Acetylcysteine increases local nitric oxide concentrations, and this vasodilatory effect on microcirculatory blood flow enhances local oxygen delivery to peripheral tissues. These vasodilating effects decrease morbidity and mortality even in the setting of established liver damage.

Acetylcysteine Recommendations
Acetyl cysteine is sold in dosages ranging from 250 to 600 mg. Acetylcysteine can help form the powerful antioxidant glutathione but the formation of glutathione synthesis is under feedback control. Administration of acetylcysteine with the resulting increase in glutathione levels may cause a feedback inhibition in glutathione synthesis. Thus, it may be best to take acetylcysteine every other day. The use of acetylcysteine certainly should be considered as an additional supplement in protecting various cells from damage in the elderly and those with Parkinson’s disease. If you are planning to use acetylcysteine along with other antioxidants, limit your daily dosage to 100 to 500 mg and don’t take it all the time. Acetylcysteine could protect the liver in those who take acetaminophen on a regular basis.

 


Guide ID: 10000000001960018Guide created: 10/02/06 (updated 12/07/07)

 
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