Most people don't know that Buckskin is washable in cold water. BUT, PLEASE, wash only if absolutely necessary. Spot-clean with a wet washcloth when possible. Sometimes an artist's eraser will bring out a stain, but don't go at it like fighting fire! Always be GENTLE on your skins!  Just never, never use a liquid detergent on skins, nor one with bleach! Some colors may bleed or fade, especially red or black, een with a plain water daubing. We don't have any COLORED buckskins, but we've heard horror stories from those who did, & those dyes will really "paint" your tub!

We use Ivory, a laundry detergent formualted for baby things. Though I have heard some say they toss their skins in a delicate-cycle wash, I wouldn't risk something as expensive or unique as buckskins to ANY automatic washer. If your garment is also BEADED, you won't want to throw those into a machine, & you had better think twice about washing them, period!
We always wash by hand in a bathtub.Yes, it's a lot of trouble, but it beats dragging those skins down to the river & pounding them on a rock!
If you DO decide to risk those beloved Buckskins in a machine wash, make SURE it's in cold water, & make doubly sure your setting is on delicate. Rinse until the water is crystal clear. Soap dries even the softest skins, & soap residue will stiffen the natural suppleness of garments made with skins. After washing, use your fingers to sort of comb & straighten any fringe or edges. Be very gentle on older skins especially, as fringe is usually the firstthing to break up.

Never, NEVER wring skins! Gently squeeze them, or, if you dare, tumble them on a NO-HEAT spin cycle for a bit, remove them to a flat surface when the extreme excess water is gone, smooth as much as possible, & rack dry, or, if the garment is not heavy, hang to dry on padded hangers, or drape over a wooden dowel rod. Be careful about hanging buckskins, their weight can make them sag all out of shape.NEVER place drying skins in direct sunlight! 
Keep away from high heat as it hardens the leather and ruins the sinew or thread.
Don't store your skins until you're 100% certain they are dry! Dampness on buckskins is a sure-fire way to have a colony of mold move in!

The absolute BEST way to dry your own personal buckskins is to WEAR them dry.Yes, just put on the wet skins & find something to do until they're dry! You'll be surprised how well they fit you after they dry! We do NOT recommend you attempt this in WINTER! Maybe a nice warm summer day with a slight breeze...? Contrary to popular thought, leather is NOT hot, even in summer. Ask anybody who wears skins a lot. Leather was once the skin of a live animal, so it breathes just like human skin does.

Hate to be the bearer of bad tidings, but GREASE does not wash out of skins & you can't make it wash out! Grease will usually wear out, some day, eventually, MAYBE.Grinding on a grease spot will just make it grow. Accept this & go on with life.

NEVER put buckskins in plastic, not in ANYTHING that contains plastic! Keep skins folded in wooden boxes as wood can also "breathe". Another option is to hang, or drape skins in a well-ventilated closet. Please treat all leathers with this kind of care. IF you do find a moldy spot on your skins, IMMEDIATELY apply a little white vinegar to the area, no need to saturate it, and bring the skins out into indirect sunlight for awhile. Don't worry, the vinegar smell will be gone before you know it!

Stay off concrete & asphalt with your moccasins. Tar will NOT come out of leather.

Although buckskins do not absorb body odors,( unless you're really, really in need of a bath) it does pick up food odors, especially spoiled milk smell. Spot clean immediately if you get a spill on your skins.

If you have an unfortunate  mishap & your skins are REALLY stain-damaged or filthy, you MAY need the help of a professional cleaner's services. Just be sure to know what sort of skin you have so you can pass that info on to the professionals.

Buckskins, & indeed all leather, can last a lifetime & then some, if you just take proper care of them & remember where they come from. Skin is skin. Treat with gentle care!