The Frontline or Advantage you buy from other countries is the same.........I've used Advantage from Australia for 5 years and have never seen a flea !  The only difference is our EPA regulations that are set for the U.S.   Do you really think they're going to make a different product for a different country? No, it's the same product........companies like that don't have different formulas, just different regulations...and approval systems......the U.S. demands the EPA registration.........that's the only difference.  As for ticks, skip the topicals and go with a preventic collar..............miles apart in performance !